Polynucleotides: What Should You Expect from the Procedure? 💉
- david lucey
- Apr 25
- 2 min read

If you're looking for a subtle yet powerful skin boost with minimal downtime, and located in Dublin or Kildare area, this could be the perfect treatment for you
If you're considering a polynucleotide treatment, you're likely curious about what the experience actually involves, from preparation to aftercare. Here's everything you need to know before your appointment.
How to Prepare?
Preparation is simple and low-stress. Ideally, you should:
Avoid coffee and alcohol for 24 hours before your treatment to help reduce the risk of bruising ☕🍷
Arrive without makeup, if possible 💄🚫
*But don’t worry, if needed, it can be removed at the clinic just before the procedure
These small steps can make your experience smoother and help support better results.
What Happens During the Procedure?
The treatment itself is relatively quick and minimally invasive 👨⚕️
There are different techniques practitioners may use. At my clinic, I prefer using a very fine meso-needle. This allows me to “pepper” the face with tiny, precise injections, distributing small volumes of product for maximum rejuvenating benefits
While some professionals use a cannula, my method targets specific areas with more control and precision, especially effective for polynucleotide delivery
Does It Hurt? Will I Bruise?
Discomfort is minimal. I apply a local anaesthetic to sensitive areas to ensure you're comfortable throughout the session 💆♀️
Because the needles I use are extremely short, bruising tends to be minimal. However, it's still possible, especially around the eyes, a particularly vascular area.
As I often tell patients, you're more likely to get a tiny bruise than to walk away without one
🌼 Tip: Arnica cream can be helpful in reducing bruising and supporting faster recovery.
What About Downtime?
There’s very little! The main things to remember after the procedure are:
Avoid rubbing your face
Don’t apply makeup immediately afterward
Keep the treated area clean to prevent irritation or infection
*A full list of aftercare recommendations will be provided during your appointment
Most clients are more or less back to normal by the next day, looking refreshed and feeling confident.
Final Thoughts
Polynucleotide therapy is one of the most innovative approaches in regenerative aesthetics. It’s quickly becoming a client favourite thanks to its natural, long-term benefits.
If you're looking for a subtle yet powerful skin boost with minimal downtime, and located in Dublin or Kildare area, this could be the perfect treatment for you
Comments